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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9541 | CTB | Cholera Toxin B subunit | Epigenetic Reader Domain |
CTB (Cholera Toxin B subunit) is an activator of p300 histone acetyltransferase and induces apoptosis in MCF-7 cells. | |||
TN2105 | Proscillaridin A | Topoisomerase | |
Proscillaridin A is a natural product.It is a potent poison of topoisomerase I/II activity with IC50 values of 30 nM and 100 nM, respectively. | |||
T15578 | Indotecan | NSC-724998,LMP-400 | Topoisomerase |
Indotecan (LMP-400) is an effective inhibitor of topoisomerase 1(Top1) (IC50: 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively). | |||
TQ0134 | Podocarpusflavone A | Topoisomerase | |
Podocarpusflavone A is a DNA topoisomerase I inhibitor. It has moderated anti-proliferative activity induce cell apoptosis in MCF-7. | |||
TN3049 | 4-Methoxycinnamyl alcohol | Others | |
4-Methoxycinnamyl alcohol showed toxicity to MCF-7, HeLa and DU145 cancer cell lines with IC50 values of 14.24, 7.82 and 22.10 μg/mL, respectively. 4-Methoxycinnamyl alcohol was isolated from Foeniculum vulgare. 4-Methox... | |||
TMS0879 | Asiaticoside B | Others | |
Asiaticoside B is a triterpene glycoside isolated from Actaea asiatica. It has notable cytotoxicity against HepG2 and MCF-7 cancer cell lines. | |||
T1166 | Ellipticine | NSC 71795,Elliptisine | Topoisomerase |
Ellipticine (Elliptisine) is a potent antineoplastic agent exhibiting multiple mechanisms of action, IC50 of 0.67±0.06, 1.25±0.13, 1.25±0.13, 0.67±0.06, 0.27±0.02, 0.49±0.04, 0.44±0.03, and 1.48±0.62 μM for Leukemia HL-6... | |||
T36970 | STD1T | DUB | |
STD1T is a selective and potent inhibitor of the deubiquitinase USP2a with potential anticancer activity that reduces cell cycle protein D1 protein levels in HCT116 colon and MCF-7 breast cancer cells. | |||
T77718 | FAK-IN-10 | FAK | |
FAK-IN-10 is an inhibitor of FAK (IC50:76.3 μM).FAK-IN-10 z MCF-7 and A431 cell lines showed antitumor activity with IC50 of 4.23 and 0.78 μM, respectively. | |||
T21804 | GW 610 | Others | |
GW 610 is an antitumor benzothiazole that shows growth-inhibitory activity against several cancer cell lines. In MCF-7 and MDA 468 human cancer cell lines, potent antiproliferative activity (growth inhibition (GI50) < 0.... | |||
T4519 | Alisol A | Alisol-A | Autophagy |
Alisol A (Alisol-A) may be an autophagic inducer, it has anti-cancer activity, it presents inhibitory effects on cancer cell lines tested(HepG2, MDA-MB-231, and MCF-7 cells). | |||
T8724 | 6-Methoxydihydrosanguinarine | Others | |
6-Methoxydihydrosanguinarine is a natural product. 6-Methoxydihydrosanguinarine shows strong cytotoxicity against MCF-7 and SF-268 cell lines with IC50 values of 0.61 μM and 0.54 μM, respectively.It has antibacterial act... | |||
T83627 | Pim-1 kinase inhibitor 8 | Pim , PKC | |
Pim-1 kinase inhibitor 8 is a potent Pim-1 kinase inhibitor with anticancer activity and can effectively inhibit cell migration.Pim-1 kinase inhibitor 8 is cytotoxic to MCF-7 and HepG2 cells, and is a candidate compound ... | |||
T2S0265 | Robinin | NSC 9222 | TLR |
Flavone glycoside from Robinia with antibacterial and diuretic properties; derived from kaempferol.The ability of robinin to reverse the multidrug resistance of the human colon cancer cell line Colo 320 expreβing MDR1/LR... | |||
T5350 | JG-98 | JG98,JG 98 | Apoptosis , HSP |
JG-98 is an allosteric Hsp70 inhibitor, displays high active against the breast cancer cell lines MDA-MB-231 and MCF-7 (EC50s: 0.4/0.7 μM). | |||
TN1727 | Helichrysetin | Apoptosis , HIV Protease | |
Helichrysetin has mild anti-HIV-1 PR activity. Helichrysetin has great potentials for development as an anticancer agent, it has cytotoxic effect on four selected cancer cell lines, A549, MCF-7, Ca Ski, and HT-29. | |||
T5724 | Neogambogic acid | neo-gambogic acid | Apoptosis , Others , Antibacterial |
Neogambogic acid, an active ingredient in garcinia, can inhibit the growth of some solid tumors and result in an anticancer effect, it may be responsible for the inhibition of proliferation of human breast cancer cell li... | |||
T5S1607 | Morusin | Mulberrochromene | NF-κB , Antibacterial , STAT |
1. Morusin (Mulberrochromene) possesses antitumor effects of cell lines including HT-29, A549, MCF-7, and MDA-MB-231, through suppressing STAT3 and NFκB attenuation mediated apoptosis induction. 2. Morusin possesses anti... | |||
T5S0506 | Rotundic acid | Rutundic acid | Apoptosis , Others , p38 MAPK , Akt , mTOR |
Rotundic acid (Rutundic acid), a natural compound, exhibit cytotoxic activities toward human hepatocellular carcinoma (HepG2), malignant melanoma (A375), SCLC (NCI-H446), breast cancer (MCF-7), and colon cancer (HT-29) c... | |||
TN2755 | 2-Desoxy-4-epi-pulchellin | Anti-infection | |
2-Desoxy-4-epi-pulchellin has potent in vitro cytotoxicities against the K562, MCF-7, Hela, DU145, U937, H1975, SGC-7901, A549, MOLT-4, and HL60 cell lines with IC50 values ranging from 0.10 to 46.7uM, while it shows sig... |